PUBLICATION

February 26, 2018

InSysBio continues to investigate the mechanisms underlying Alzheimer’s disease (AD) using the quantitative systems pharmacology (QSP) modeling approach. The part of QSP model describing tau protein was published in the PLOS ONE journal. This is one of more than dozen InSysBio publications in AD area during last seven years.

Read more about InSysBio modelers evaluated tau protein phosphorylation related targets for Alzheimer’s disease treatment

Computer model showed an optimal anti-amyloid treatment

Moscow, Russia, September 28, 2017. One must activate amyloid degradation as soon as possible to prevent the appearance of the protein plaques in brain under Alzheimer’s conditions. This conclusion was reached by scientists from the biotechnology company InSysBio, who created the first computer model of the disease. The final part of the work has been recently published in CPT: Pharmacometrics & Systems Pharmacology.

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To predict unpredictable: a platform for modeling of the high-selective oncology drugs was created

Moscow, Russia, July 14, 2017. The scientists from BIND RUS and InSysBio (www.insysbio.ru) published a joint research of the new class of anti-oncology treatment in the Journal of Controlled Release. Unique nanoparticles enriched with medications can deliver its content targeted to the tumor site, and the parameters of their effectiveness are programmed during the forming phase.

Read more about To predict unpredictable: a platform for modeling of the high-selective oncology drugs was created

System pharmacology modelers throw light on drug discovery in Alzheimer's

Moscow, Russia - 21 June, 2017. InSysBio scientific group led by Tatiana Karelina developed a quantitative system pharmacology model of Alzheimer’s disease. First part published in CPT PSP shows how to design initial phases of clinical trials of new drugs and to interpret the data obtained.

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A New Mathematical Model of the Eosinophil Lifecycle Shows Irrelevance of the Asthma Biomarker Choice

Moscow, Russia - November 29th, 2016. Institute for Systems Biology Moscow (www.insysbio.ru), one of the pioneers in bio-modeling and simulation announced the study made in collaboration with scientists of two pharmaceutical leaders: MedImmune and AstraZeneca.